SIRT1 mRNA expression may be associated with energy expenditure and insulin sensitivity.

 

SIRT1 mRNA expression may be associated with energy expenditure and insulin sensitivity.

Show full item record

Title: SIRT1 mRNA expression may be associated with energy expenditure and insulin sensitivity.
Author: Rutanen, Jarno; Yaluri, Nagendra; Modi, Shalem; Pihlajamäki, Jussi; Vänttinen, Markku; Itkonen, Paula; Kainulainen, Sakari; Yamamoto, Hiroyasu; Lagouge, Marie; Sinclair, David A; Elliott, Peter; Westphal, Christoph; Auwerx, Johan; Laakso, Markku
Abstract: Sirtuin 1 (SIRT1) is implicated in the regulation of mitochondrial function, energy metabolism, and insulin sensitivity in rodents. No studies are available in humans to demonstrate that SIRT1 expression in insulin-sensitive tissues is associated with energy expenditure and insulin sensitivity.
Citation: Diabetes. 2010 Apr;59(4): 829-35. EPub 2010 Jan 27
PMC: http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=20107110

This item appears in the following Collection(s)

Show full item record